Ariane Caldas
Secretaria de Apoio Social ao Cidadão
O Cras Eugênio de Melo reuniu na tarde desta sexta-feira (22) diversas atividades em conscientização ao Dia Internacional de Combate à Discriminação Racial, celebrado em 21 de março.
A ação teve inicio com uma roda de conversa sobre letramento racial. As crianças participaram ativamente e contribuíram levantando questões do dia a dia. O objetivo foi explicar e conscientizar os pequenos sobre expressões que podem transmitir estereótipos, preconceitos ou discriminações.
Para o Yuri Cauã Moreira da Silva foi um momento para aprender um pouco mais sobre como combater o racismo. Aos 10 anos, ele já sabe como a luta é importante. “As pessoas acham que são melhores que as outras pela cor, mas não é assim, tem que respeitar”, disse.
Já Manuelle Mesquita Pereira, 10 anos, a melhor forma de acabar com o preconceito é com informação. “Tem que falar para todo mundo, postar vídeo e tudo mais”, destacou.
Durante a tarde, os participantes também aprenderam a fazer as bonecas Abayomi, confeccionadas com retalhos de tecidos, elas são símbolo de força e resistência da cultura africana.
O Cras também recebeu a exposição itinerante Beleza dos Tons, com 20 imagens de mulheres negras captadas pela fotógrafa joseense Larissa Isis.
Até o fim do mês, as atividades serão desenvolvidas em outros equipamentos da assistência social. Confira a galeria de fotos.
MAIS NOTÍCIAS
Secretaria de Apoio Social ao Cidadão
Beginners Anabolic Cycle
Beginner‑Level Testosterone Replacement Program (TRT)
Prepared for clinicians who want a concise, evidence‑based reference that does not endorse
specific brands.
—
1. Core Principles
Principle Rationale
Individualized dosing Patients differ in age, comorbidities, baseline
hormone levels, and response to therapy. Start low, titrate up.
Monitoring for efficacy & safety Regular labs (total testosterone, free/estradiol, CBC, CMP) and symptom tracking are mandatory.
Adjunct care Address lifestyle factors (nutrition, exercise,
sleep), treat underlying conditions (hypothyroidism, sleep apnea),
and consider bone density or cardiovascular risk if indicated.
—
2. Baseline Work‑Up
History & Physical
– Symptoms: libido loss, fatigue, mood changes, erectile dysfunction,
muscle weakness, gait instability.
– Comorbidities: diabetes, hypertension, obesity, sleep apnea, psychiatric illness.
Laboratory Panel
| Test | Purpose |
|——|———|
| Total testosterone (morning 7‑10 am) | Baseline
hormone level |
| LH & FSH | Differentiate primary vs secondary hypogonadism |
| Estradiol | Detect estrogen excess in men on aromatase
inhibitors |
| Prolactin | Rule out pituitary causes |
| CBC, CMP | Baseline organ function |
| PSA | Baseline prostate status (important
for future monitoring) |
Imaging
– Pituitary MRI if clinical features of pituitary
dysfunction or abnormal LH/FSH.
– Brain CT/MRI if neurological symptoms present.
Special Tests
– If hypogonadism suspected, perform a hCG stimulation test to confirm Leydig cell function.
2. Hormonal Evaluation and Interpretation
Test Normal Range (adult male) Clinical Relevance
LH 1–8 IU/L Low LH → primary hypogonadism; high LH → secondary failure
FSH 1.5–12 IU/L Similar interpretation as LH
Testosterone (total) 300–1000 ng/dL Hypo‑ or hyperandrogenic states
Estradiol (E2) 38 °C, chills, or pain that worsens, seek emergency care (ER)
as these could indicate infection requiring antibiotics.
Seek urgent outpatient care: Many clinics offer
same‑day appointments; contact a local urgent‑care clinic or walk‑in office and explain your symptoms.
Bring your medical record if possible.
4. How to “Know” You’re Sick vs. Feeling Unwell
Symptom Likely Infection (needs evaluation) Likely General Malaise/Stress
Fever >38 °C, chills, sweating Yes – seek care No
Rapid breathing, shortness of breath Yes – urgent assessment No
Chest pain or pressure Yes – evaluate for cardiac causes No
Persistent cough with sputum (especially if foul‑smelling)
Yes – could be bacterial Mild
Severe headache + stiff neck Yes – meningitis risk No
Confusion, dizziness, weakness Yes – monitor closely May
improve with rest
Generalized body aches & fatigue that improves over days
No – likely viral recovery Yes
—
Bottom line
Treat as you would a mild bacterial sinus infection: use an appropriate antibiotic (e.g., amoxicillin‑clavulanate
500 mg/125 mg BID for 10 days).
Give supportive care (acetaminophen or ibuprofen, saline nasal
rinses, adequate fluids, rest).
Watch for red flags. If symptoms worsen, you develop high fever (>38.5 °C), severe facial pain, swelling,
vision changes, confusion, or if symptoms persist beyond 10–14 days,
seek urgent medical care.
This plan balances the likelihood of a bacterial infection with judicious
antibiotic use and close monitoring for complications.
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After just two weeks of using Anavar, many users—especially women—begin to notice
subtle yet encouraging changes that set the tone for the rest of their cycle.
The early effects are often a mix of improved body composition, increased energy levels,
and mild aesthetic enhancements that make the commitment feel worthwhile.
Anavar Results After 2 Weeks For Females
During the first fortnight, most female users report an immediate
boost in stamina during workouts, allowing them to push through sets with greater confidence.
Because Anavar is known for its gentle nature compared to other anabolic steroids, women typically
experience a reduction in body fat that manifests as a more toned midsection and slimmer waistline.
Muscle definition starts to become visible, particularly around the arms,
shoulders, and calves. Even though significant muscle growth usually takes
longer, the early weeks provide a noticeable tightening of soft tissues,
giving users a clearer sense of progress.
Anavar for Women
Women often choose Anavar for its low androgenic activity, which minimizes the risk of virilization—a common concern with
more potent steroids. The compound’s mild nature means that
side effects such as acne or hair loss are usually mild and manageable when proper skin care is followed.
For those looking to enhance athletic performance without
drastic weight gain, Anavar offers a balanced approach: it supports
lean muscle retention while promoting fat loss. Many female athletes report feeling lighter and
more agile after just two weeks, which translates into better sprint times, improved
endurance, and quicker recovery between sessions.
Average Dosage
The recommended starting dose for women is
typically lower than for men due to differences in body composition and hormone sensitivity.
A common regimen begins at 10 mg per day for the first week
and may increase to 20–25 mg per day by the second week, depending on individual
tolerance. Some users find that staying within this range provides sufficient stimulus for fat loss while keeping side effects minimal.
It is essential to monitor how your body reacts; if any signs
of excess virilization or liver strain appear, reducing the dose
or stopping the cycle is advised.
In summary, after two weeks on Anavar, female users can expect enhanced workout
performance, visible muscle definition, and a reduction in body fat—all achieved
with a dosage that prioritizes safety. These early results are often enough to motivate continued use while maintaining awareness of personal limits and
health considerations.
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CJC 1295 and Ipamorelin are two peptides that
have attracted attention in the fields of anti‑aging, sports performance, and medical research due to their
potential to stimulate growth hormone release. While many
users report benefits such as increased muscle mass, improved
recovery, and enhanced fat loss, it is essential to be aware of possible side effects associated with these compounds.
This guide provides a thorough overview of the known adverse reactions, mechanisms behind them, and practical
tips for minimizing risk.
CJC 1295 Ipamorelin Side Effects: A Comprehensive Guide
Understanding CJC 1295 Ipamorelin
What Are CJC 1295 and Ipamorelin?
The following sections break down each aspect of these peptides so that you can make an informed decision about their
use.
Understanding the Basics
Mechanism of Action
Common Side Effects
Rare or Severe Reactions
Long‑Term Considerations
Managing and Mitigating Risks
1. Understanding the Basics
CJC 1295 is a synthetic growth hormone‑releasing hormone analogue that binds to receptors in the pituitary gland,
prompting the secretion of growth hormone (GH) and insulin‑like growth
factor‑1 (IGF‑1). tesamorelin ipamorelin blend side effects is
a ghrelin receptor agonist that also stimulates GH release but with a different binding profile.
When used together, they are believed to provide synergistic stimulation of endogenous
GH production.
Because these peptides act on hormonal pathways, the side effect profile often mirrors other growth hormone
therapies such as recombinant human GH or long‑acting analogues.
The most frequently reported issues involve fluid retention, joint discomfort, and changes in metabolic parameters.
—
2. Mechanism of Action
CJC 1295 increases circulating GH by mimicking natural GHRH.
Its extended half‑life allows for sustained stimulation after a single injection per week.
Ipamorelin mimics ghrelin, the “hunger hormone,” but is selective for GH release without significantly affecting
appetite or cortisol levels.
Together they produce higher peaks of GH and IGF‑1 than either agent alone.
This amplified effect can amplify both desired outcomes (muscle growth, fat loss) and unwanted side effects.
3. Common Side Effects
The following adverse reactions are reported by a majority of users who take CJC 1295 or Ipamorelin in standard dosing regimens:
3.1 Injection Site Reactions
Redness, swelling, or mild pain at the injection site
Rarely, bruising or small hematomas
Occur more often when injections are given subcutaneously
3.2 Fluid Retention (Edema)
Swelling in extremities, especially ankles and feet
Mild bloating or puffiness of the face
Can be mitigated by staying hydrated and
using compression stockings
3.3 Joint and Muscle Pain
Aching shoulders, knees, hips, or lower back
Often described as “tightness” rather than sharp pain
Usually resolves after a few days of use or when dosage is
reduced
3.4 Headaches and Migraine Triggers
Mild to moderate throbbing headaches
May be related to changes in blood pressure or
fluid balance
3.5 Fatigue and Sleep Disturbances
Some users report feeling drowsy during the day or having trouble falling asleep at night
Adjusting injection timing (e.g., early morning vs late evening)
can help
3.6 Increased Appetite or Weight Gain
Though Ipamorelin is less appetite‑stimulating than other ghrelin analogues,
some users notice a slight increase in hunger
The effect is usually modest and can be countered with
balanced nutrition
3.7 Skin Changes
Occasional acne flare-ups or increased oiliness
Mild redness or flushing after injection
4. Rare or Severe Reactions
Although uncommon, certain serious side effects have been documented in clinical studies and
anecdotal reports:
4.1 Hypoglycemia
Growth hormone can counteract insulin action, potentially raising blood glucose levels
In rare cases, the opposite effect—lowered glucose—has been observed, especially when combined with other hormonal agents
4.2 Hypertension or Cardiovascular Stress
Elevated blood pressure readings have been noted in a small subset of users
Monitoring systolic and diastolic pressures before starting
therapy is advisable
4.3 Carpal Tunnel Syndrome
Repeated GH stimulation may increase fluid around the wrist, leading to nerve compression symptoms
4.4 Thyroid Dysfunction
Some patients experience changes in thyroid hormone levels; routine screening can catch early abnormalities
4.5 Hormonal Imbalance in Women
In women, excessive GH release may alter menstrual cycles or lead to ovarian cysts
Hormone‑monitoring protocols are recommended for female users
5. Long‑Term Considerations
The long‑term safety profile of CJC 1295 and Ipamorelin remains under investigation. Potential concerns include:
Cancer Risk: Elevated IGF‑1 levels have been linked to
increased proliferation in certain cell types, though definitive evidence for these peptides is limited.
Endocrine Resistance: Prolonged overstimulation may blunt the
body’s natural GH production pathways.
Metabolic Alterations: Chronic use could affect insulin sensitivity and lipid profiles.
For users considering extended therapy (more than 12–18 weeks),
periodic medical evaluation—including blood tests for liver enzymes,
thyroid function, fasting glucose, and lipid panels—is strongly recommended.
6. Managing and Mitigating Risks
Below are practical strategies to reduce the likelihood of adverse reactions:
Start Low, Go Slow
– Begin with a minimal dose (e.g., 100–150 µg per injection) and gradually increase only if tolerated.
Monitor Injection Technique
– Use clean needles, rotate sites regularly, and keep injections at a consistent angle to avoid bruising.
Hydration and Electrolytes
– Drink plenty of water and consider electrolytes (magnesium, potassium) to counter fluid
retention.
Timing of Injections
– Administer in the morning to align with natural circadian GH
peaks and reduce nighttime sleep disturbances.
Dietary Adjustments
– Limit high‑sugar foods that may interfere with insulin sensitivity; focus on balanced protein, healthy fats,
and complex carbohydrates.
Regular Health Checks
– Schedule blood work every 3–6 months to track GH, IGF‑1, glucose, thyroid, and lipid levels.
Use of Adjunctive Therapies
– Some users incorporate antioxidants or anti‑inflammatory
supplements (e.g., turmeric, omega‑3s) to ease
joint discomfort.
Awareness of Symptoms
– Recognize early signs of severe reactions such as sudden swelling, chest pain, fainting, or persistent headaches and seek
medical help promptly.
Conclusion
CJC 1295 and Ipamorelin offer a potent means of stimulating
natural growth hormone production, with benefits
that appeal to both athletes and individuals seeking anti‑aging effects.
However, the hormonal manipulation involved carries a spectrum of side effects—from mild injection site irritation to
more serious cardiovascular or endocrine disturbances.
By understanding these risks, starting conservatively,
monitoring health parameters closely, and adopting supportive lifestyle measures, users can maximize benefits while minimizing potential
harm.
—
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